Molecular and Cellular Engineering Lab

연구실 소개

From Data to Delivery: Precision-Engineered AAV Gene Therapy Bridging Discovery, Delivery, and Patients —Where Gene Therapy Principles Become Patient-Ready Solutions. The laboratory develops next-generation AAV-mediated gene delivery systems through an integrated framework that combines directed evolution, rational vector design, and biomaterial-mediated delivery strategies. They focus on high-precision in vivo targeting across a broad range of biologically and clinically challenging tissues and integrate immune-evasive AAV engineering, scalable vector manufacturing and purification, and large-animal validation. Machine learning and artificial intelligence are used for data-driven solutions in gene therapy development, leveraging large-scale experimental datasets and structure-based AI approaches.