The Pattern Recognition & Bio-intelligence Lab researches core technologies in pattern recognition, machine learning, deep learning, computer vision, and medical artificial intelligence, and based on these, develops intelligent systems to solve various real-world problems. In particular, we aim to contribute to the improvement of human health by applying artificial intelligence technology to bio and medical fields such as medical image analysis, biosignal processing, disease diagnosis and prediction, and new drug development.

패턴인식 및 바이오 지능 연구실은 패턴인식, 기계학습, 딥러닝, 컴퓨터 비전, 의료 인공지능 분야의 핵심 기술을 연구하며, 이를 기반으로 다양한 실제 문제 해결을 위한 지능 시스템을 개발하고 있습니다. 특히, 의료 영상 분석, 생체 신호 처리, 질병 진단 및 예측, 신약 개발 등 바이오 및 의료 분야에 인공지능 기술을 접목하여 인류의 건강 증진에 기여하는 것을 목표로 합니다.

Dark Matter benchmark models for early LHC Run-2 Searches: Report of the ATLAS/CMS Dark Matter Forum

Advancing LHC probes of dark matter from the inert two-Higgs-doublet model with the monojet signal

Measurements of an AC-LGAD strip sensor with a 120 GeV proton beam

Combined analysis of HPK 3.1 LGADs using a proton beam, beta source, and probe station towards establishing high volume quality control

Observation of a shadow of the Moon in the underground muon flux in the Soudan 2 detector

Pulse shape discrimination using a convolutional neural network for organic liquid scintillator signals

Pulse-shape Discrimination of Fast Neutron Background using Convolutional Neural Network for NEOS II

The Analog Front-end for the LGAD Based Precision Timing Application in CMS ETL

The ETROC Project: Precision Timing ASIC Development for LGAD-based CMS Endcap Timing Layer (ETL) Upgrade

Background studies for the CODEX-b experiment: measurements and\n simulation

t-channel dark matter models – a whitepaper

Performance of the missing transverse energy reconstruction by the CMS experiment in sqrt(s) = 8 TeV pp data

Production of single top quark - results from the Tevatron and the LHC

Publisher Erratum: t-channel dark matter models – a whitepaper

Top quark pair production and top quark properties at CDF

Top Physics at CDF

Searches for heavy scalar and pseudoscalar Higgs bosons and for flavor-violating decays of the top quark into a Higgs boson in pp collisions at $\sqrt{s}$ = 8 TeV

A level-1 pixel based track trigger for the CMS upgrade

Large-Scale Deep Learning for Multi-Jet Event Classification

Multi-Jet Event classification with Convolutional neural network at Large Scale

Multi-modal Retinal Disease Classification Using Fundus and OCT Images with Vision Transformer and Self-Attention Feature Fusion

Deep Learning-Based Prediction Model for Parkinson’s Disease Progression Using Time-Series Clinical Data

Few-Shot Learning for Medical Image Classification Using Vision Transformer with Prototype Network

Explainable AI for Early Detection of Alzheimer’s Disease Using Multi-Modal Brain Imaging Data

Effect of single xeno-nucleic acid replacement on the fluorescence of DNA-encapsulated silver nanoclusters

O-GlcNAcylation of XRCC4 controls its stability and confers resistance to DNA double-strand break damage in cancer cells

PNPLA3 I148M is unrelated to HCC occurrence but associates with poorer tumor differentiation in Korean MASLD: a prospective cohort of 562 patients

Identification of specific miRNAs in early-stage mung bean (Vigna radiata) using DNA/AgNCs sensors and miRNAtome analysis

The chloroplast-targeted long noncoding RNA CHLORELLA mediates chloroplast functional transition across leaf ageing via anterograde signalling

Dasineura asteriae Reprograms the Flower Gene Expressions of Vegetative Organs to Create Flower-Like Gall in Aster scaber

The PNPLA3 I148M variant is associated with immune cell infiltration and advanced fibrosis in MASLD: a prospective genotype-phenotype study

O-GlcNAcylation of NONO regulates paraspeckle component assembly and contributes to colon cancer cell proliferation

Application of fluorescence i-motif DNA silver nanocluster sensor to visualize endogenous reactive oxygen species in plant cells

Energy Transfer Between i-Motif DNA Encapsulated Silver Nanoclusters and Fluorscein Amidite Efficiently Visulaizes the Redox State of Live Cells

Tailed-Hoogsteen Triplex DNA Silver Nanoclusters Emit Red Fluorescence upon Target miRNA Sensing

Circulating Extracellular-Vesicle-Incorporated MicroRNAs as Potential Biomarkers for Ischemic Stroke in Patients With Cancer

The HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE15-HISTONE DEACETYLASE9 complex associates with HYPONASTIC LEAVES 1 to modulate microRNA expression in response to abscisic acid signaling

Genome-wide signatures of adaptation to extreme environments in red algae

The nucleolus is the site for inflammatory RNA decay during infection

Silver Nanoclusters Serve as Fluorescent Rivets Linking Hoogsteen Triplex DNA and Hairpin-Loop DNA Structures

Circulating microRNAs differentially expressed in Koream Alzheimer's patients with brain Aβ accumulation activate amyloidogenesis

Transcriptome analysis revealed that jasmonic acid biosynthesis/signlaing is involved in plant response to Strontium stress

Circulating Extracellular Vesicles in Stroke Patients Treated with Mesenchymal Stem Cells: A Biomarker Analysis of Randomized Trial

HYL1-CLEAVAGE SUBTILASE 1 (HCS1) Suppresses miRNA biogenesis in response to light-to-dark transition

Light-Stablized FHA2 suppresses miRNA biogenesis through interactions with DCL1 and HYL1

Strontium stress disrupts miRNA biogenesis by reducing HYL1 protein levels in Arabidopsis

Formation and Structure of Fluorescent Silver Nanoclusters at Interfacial Binding Sites Facilitating Oligomerization of DNA Hairpins

Noncanonical Head-to-Head Hairpin DNA Dimerization Is Essential for the Synthesis of Orange Emissive Silver Nanoclusters

Light Triggers the miRNA-Biogenetic Inconsistency for De-etiolated Seedling Survivability in Arabidopsis thaliana

Enrichment of Exosome-Like Extracellular Vesicles from Plasma Suitable for Clinical Vesicular miRNA Biomarker Research

Dynamic Regulation of miRNA expression by Functionally Enhanced Placental Mesenchymal Stem Cells PromotesHepatic Regeneration in a Rat Model with Bile Duct Ligation

Keep calm and carry on: miRNA biogenesis under stress

Inverse Correlation Between MPSR1 E3 Ubiquitin Ligase and HSP90.1 Balances Cytoplasmic Protein Quality Control

Classification of barley U-box E3 ligases and their expression patterns in response to drought and pathogen stresses

Structural Influence on the Post-Clustering Stability of DNA/AgNCs Fluorescence

A Quick HYL1-Dependent Reactivation of MicroRNA Production Is Required for a Proper Developmental Response after Extended Periods of Light Deprivation

Synthetic MicroProteins: Versatile Tools for Posttranslational Regulation of Target Proteins

BPH1, a novel substrate receptor of CRL3, plays a repressive role in ABA signal transduction

Diurnal regulation of cyanogenic glucoside biosynthesis and endogenous turnover in cassava

MPSR1 is a cytoplasmic PQC E3 ligase for eliminating emergent misfolded proteins in Arabidopsis thaliana

Optimization of Agrobacterium-mediated transient expression of heterologous genes in spinich

AtAIRP2 E3 Ligase Affects ABA and High-Salinity Responses by Stimulating Its ATP1/SDIRP1 Substrate Turnover

Development of a virus-induced gene silencing (VIGS) system for Spinacia oleracea L.

RING E3 ligases: Key regulatory elements are involved in abiotic stress responses in plants

KETCH1 imports HYL1 to nucleus for miRNA biogenesis in Arabidopsis

HIGLE is a bifunctional homing endonuclease that directly interacts with HYL1 and SERRATE in Arabidopsis thaliana

MicroRNA Biomarkers in Neurodegenerative Diseases and Emerging Nano-Sensors Technology

Regulation of MIR165/166 by class II and class III homeodomain leucine zipper proteins establishes leaf polarity

Post-Translational Regulation of miRNA Pathway Components, AGO1 and HYL1, in Plants

Locking-to-unlocking system is an efficient strategy to design DNA/silver nanoclusters (AgNCs) probe for human miRNAs

Arabidopsis Toxicos en Levadura 78 (AtATL78) mediates ABA-dependent ROS signaling in response to drought stress

PUB22 and PUB23 U-BOX E3 ligases directly ubiquitinate RPN6, a 26S proteasome lid subunit, for subsequent degradation in Arabidopsis thaliana

Cesium toxicity alters microRNA processing and AGO1 expressions in Arabidopsis thaliana

DNA/RNA chimera templates improve the emission intensity and target accessibility of silver nanocluster-based sensors for human microRNA detection

COP1 E3 ligase protects HYL1 to retain miRNA biogenesis

DNA/RNA chimera indicates the flexibility of the backbone influences the encapsulation of fluorescent AgNCs emitters

Insights into the structural determinants for the formation of fluorescent silver nanoclusters on DNA, RNA and DNA-RNA chimeras

Fold-back anchor DNA-templated silver nanoclusters for miRNA detection

Multiplexed microRNA Detection Using Lanthanide-Labeled DNA Probes and Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS)

In solution multiplex miRNA detection using DNA-templated silver nanocluster probes

Gene silencing of Sugar dependent 1 (JcSDP1), encoding a patatin-domain triacylglycerol lipase, enhances seed oil accumulation in Jatropha curcas

Effect of salts, solvents and buffer on miRNA detection using DNA silver nanocluster (DNA/AgNCs) probes

Two aquaporins of Jatropha are regulated deferentially during drought stress and subsequent recovery

STA1, an Arabidopsis pre-mRNA processing factor 6 homolog, is a new player involved in miRNA biogenesis

Design Aspects of Bright Red Emissive Silver Nanoclusters/DNA Probes for MicroRNA Detection

Arabidopsis DRB4 protein in antiviral defense against Turnip yellow mosaic virus infection

Rapid detection of miRNA by a silver cluster DNA probe

Structure of Arabidopsis HYPONASTIC LEAVES1 and its molecular implications for miRNA processing

Suppression of the ER-Localized AAA ATPase NgCDC48 Inhibits Tobacco Growth and Development

LAF1 and HFR1 associate with FHY1 and FHL to transmit phyA signals for inhibition of hypocotyl elongation

Structure of the DNA-binding domain of NgTRF1 reveals unique features of plant telomere-binding proteins

Independent and interdependent functions of LAF1 and HFR1 in phytochrome A signaling

FHL is required for full phytochrome A signaling and shares overlapping functions with FHY1

A plausible model of the proteolytic regulation of HYL1 for miRNA homeostasis. Upon light exposure, COP1 shifts to the cytoplasm and suppress the cleavage of HYL1 by protease X, may be together with autophagy. In darkness, COP1 remobilizes into nucleus that unshackles the protease X. COP1 E3 ligase protects HYL1 to retain miRNA biogenesis

Pattern Recognition & Bio-intelligence Lab (PRBL)

교수님 소개

Seong Wook Yang

연구실 소개

연구실 키워드

알럼나이가 간 회사

연구실 지원 방법

대우 조건

연도별 논문 인용수

저널 & 학회 논문 출판 수

연구실 논문 목록

Effect of single xeno-nucleic acid replacement on the fluorescence of DNA-encapsulated silver nanoclusters

O-GlcNAcylation of XRCC4 controls its stability and confers resistance to DNA double-strand break damage in cancer cells

Effect of single xeno-nucleic acid replacement on the fluorescence of DNA-encapsulated silver nanoclusters

연구실 보유 특허

대학별 입시끈

우리 연구실 모집

교수님 소개

Seong Wook Yang

연구실 키워드

알럼나이가 간 회사

연구실 지원 방법

대우 조건

연도별 논문 인용수

저널 & 학회 논문 출판 수

연구실 논문 목록

Effect of single xeno-nucleic acid replacement on the fluorescence of DNA-encapsulated silver nanoclusters

O-GlcNAcylation of XRCC4 controls its stability and confers resistance to DNA double-strand break damage in cancer cells

Effect of single xeno-nucleic acid replacement on the fluorescence of DNA-encapsulated silver nanoclusters

연구실 보유 특허

최근 3년간 연구실적 높은 연구실

대학별 입시끈

우리 연구실 모집