Eun Kyung Song

Ju Yeon Hong

We study the mechanisms for shape formation during early development using
Xenopus Laevis
. Our long term goal is to understand cell biological mechanisms for the morphogenesis in various tissues. To study the mechanisms, we use several imaging techniques and also general cell and molecular biology techniques.
저희 연구실에서는 Xenopus laevis 를 동물모델로 하여 발생과정에서 조직의 형태형성을 조절하는 기작을 연구하고 있습니다.
형태형성에 관련된 세포와 분자수준의 기작을 연구하기 위해 다양한 이미징 기술과 분자, 세포생물학적 기법을 이용하고 있습니다.

저희 연구실에서는 Xenopus laevis 를 동물모델로 하여 발생과정에서 조직의 형태형성을 조절하는 기작을 연구하고 있습니다.
형태형성에 관련된 세포와 분자수준의 기작을 연구하기 위해 다양한 이미징 기술과 분자, 세포생물학적 기법을 이용하고 있습니다.

GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance

ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis.

Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis

HRP-conjugated plug-and-playable IgG-binding nanobodies as secondary antibody mimics in immunoassays

Extracellular matrixes and neuroinflammation

Alpha-tocopherol exerts protective function against the mucotoxicity of particulate matter in amphibian and human goblet cells

Simple Method To Characterize the Ciliary Proteome of Multiciliated Cells

Peroxiredoxin5 controls vertebrate ciliogenesis by modulating mitochondrial ROS

Lysine demethylase 3a in craniofacial and neural development during Xenopus embryogenesis

Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development

KDM1A microenvironment, its oncogenic potential, and therapeutic significance

Blockade of cannabinoid 1 receptor improves glucose responsiveness in pancreatic beta cells

Xenopus: An alternative model system for identifying muco-active agents

3′-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis

Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels

Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo

IFT46 plays crucial roles in craniofacial and cilia development

The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery

A Recombinant Secondary Antibody Mimic as a Target-specific Signal Amplifier and an Antibody Immobilizer in Immunoassays

Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway

Notch1 deficiency decreases hepatic lipid accumulation by induction of fatty acid oxidation

Damage-associated molecular patterns and their pathological relevance in diabetes mellitus

A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation

Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9.

Integrin β-like 1 protein (ITGBL1) promotes cell migration by preferentially inhibiting integrin-ECM binding at the trailing edge

Spectroscopic characterization of biochemical states of myoglobin in beef in different environments

An enhanced ascorbate peroxidase 2/antibody-binding domain fusion protein (APEX2-ABD) as a recombinant target-specific signal amplifier

BIX-01294-induced autophagy regulates elongation of primary cilia

Superior Ion-Conducting Hybrid Solid Electrolyte for AllSolid-State Batteries

The planar cell polarity effector protein Wdpcp (Fritz) controls epithelial cell cortex dynamics via septins and actomyosin

Integrin signaling in cartilage development

RFX2 is broadly required for ciliogenesis during vertebrate development

Planar Cell Polarity Acts Through Septins to Control Collective Cell Movement and Ciliogenesis

High-magnification in vivo imaging of Xenopus embryos for cell and developmental biology

Systematic discovery of non-obvious human disease models through orthologous phenotypes

Proc Natl Acad Sci

Whole-Mount Fluorescence Immunocytochemistry on Xenopus Embryos

Dishevelled controls apical docking and planar polarization of basal bodies in a mucociliary epithelium

Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

Subcellular localization and signaling properties of Dishevelled in developing vertebrate embryos

Cloning and characterization of TMPRSS6, a novel type 2 transmembrane serine protease

Identification and characterization of a putative homolog of a spliceosome component, precursor RNA processing 3 in Drosophila melanogaster

dELL, a drosophila homologue of transcription elongation factor ELL (eleven‐nineteen lysine rich leukemia), is required for early development

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

Planar cell polarity acts through septins to control collective cell movement and ciliogenesis

Systematic discovery of nonobvious human disease models through orthologous phenotypes

Subcellular localization and signaling properties of dishevelled in developing vertebrate embryos

Regulation of ciliary polarity by the APC/C

ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis

Whole-mount fluorescence immunocytochemistry on Xenopus embryos

3′‐Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis

Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9

Developmental Morphogenesis Lab

교수님 소개

박태주

연구실 소개

연구실 키워드

알럼나이가 간 회사

연구실 지원 방법

대우 조건

연도별 논문 인용수

저널 & 학회 논문 출판 수

연구실 논문 목록

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance

Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9.

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance

연구실 보유 특허

대학별 입시끈

우리 연구실 모집

교수님 소개

박태주

연구실 키워드

알럼나이가 간 회사

연구실 지원 방법

대우 조건

연도별 논문 인용수

저널 & 학회 논문 출판 수

연구실 논문 목록

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance

Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9.

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance

연구실 보유 특허

최근 3년간 연구실적 높은 연구실

대학별 입시끈

우리 연구실 모집