진권휴

노유진

김수지

진가연

이경희

손혜림

이선재

안태희

최연지

김한희

윤신희

전상수

장믿음

박하연

남채린

손아영

김다현

최호정

남예지

현승준

장다희

The Biointerface Structure and Skin Lab (피부 및 바이오인터페이스 구조 연구실) at DGIST studies the structure-function relationship at the molecular, cellular, and tissue levels. The lab focuses on the design of interface biosystems formed around the environment, skin, integumentary system, and related nervous and endocrine systems. Research also includes structure-based drug design utilizing protein structure and physiological knowledge. The lab designs and produces proteins, skin cells, skin tissues, and artificial skin systems useful for maintaining skin homeostasis. They investigate the homeostatic maintenance mechanisms of the skin and integumentary system from molecular to individual levels, and the structural and functional collaboration of related musculoskeletal, endocrine, and nervous biosystems. Furthermore, the lab delves into structural biology, understanding the form and function of molecular machines and macroscopic structures from atomic to molecular levels, and applying this to structure-based drug design. Based on a biological understanding of the skin, they conduct BioDesign and BioEngineering of the integumentary system, including skin proteins, cells, tissues, and artificial skin models.

피부 및 바이오인터페이스 구조 연구실에서는 분자, 세포, 조직 수준의 구조-기능 상관관계를 연구합니다. 특히, 환경과 피부, 외피계, 관련 신경계 및 내분비계를 중심으로 형성되는 인터페이스 바이오시스템의 디자인을 연구합니다. 또한, 단백질 구조와 생리학적 지식을 바탕으로 한 구조 기반 신약 설계를 진행하며, 피부 항상성 유지에 유용한 단백질, 피부세포 및 피부조직, 나아가 인공피부 시스템을 설계 제작합니다.

Gravitation and Cosmology

Regeneration of Dental-Pulp-like Tissue by Chemotaxis-Induced Cell Homing

Eosinophilic Lung Diseases: A Clinical, Radiologic, and Pathologic Overview

Electrospun PLGA nanofiber scaffolds for articular cartilage reconstruction: mechanical stability, degradation and cellular responses under mechanical stimulation in vitro

High-throughput Protein and mRNA Expression–based Classification of Gastric Cancers Can Identify Clinically Distinct Subtypes, Concordant With Recent Molecular Classifications

Expression and regulation of Toll-like receptor 2 by IL-1β and fibronectin fragments in human articular chondrocytes

Dynamic response analysis of monorail bridges under moving trains and riding comfort of trains

In-situ formation of the hydroxyapatite/chitosan-alginate composite scaffolds

Incidence of and Risk Factors for Complex Regional Pain Syndrome Type 1 after Surgery for Distal Radius Fractures: A Population-based Study

Superlocalized Three-Dimensional Live Imaging of Mitochondrial Dynamics in Neurons Using Plasmonic Nanohole Arrays

High-Strength Fiber-Reinforced Composite Hydrogel Scaffolds as Biosynthetic Tendon Graft Material

Experimental cerebral fat embolism: embolic effects of triolein and oleic acid depicted by MR imaging and electron microscopy.

Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial–mesenchymal transition of hepatocellular carcinoma

Anti-fouling performance of chevron plate heat exchanger by the surface modification

Biomechanical comparisons of three different tibial tunnel directions in posterior cruciate ligament reconstruction

Hyponatraemia induced by low-dose intravenous pulse cyclophosphamide

Ultrasonographic evaluation of the first extensor compartment of the wrist in de Quervain’s disease

Performance of the AUDIT Alcohol Consumption Questions (AUDIT-C) and AUDIT-K Question 3 Alone in Screening for Problem Drinking

The incidence of carpal tunnel syndrome in patients with rheumatoid arthritis

Surface Plasmon Localization-Based Super-resolved Raman Microscopy

A novel role of erythropoietin in skin pigmentation through melanin production

Expression and Purification of the Ectodomain of Erythropoietin Receptor Fused to mCitrine or mTFP1 Fluorescent Protein in Escherichia coli

A role for Keratin 17 in Rac1-mediated DNA damage response in keratinocytes

MLPH-mediated activation of dermal papilla IGF-1 signaling drives human hair shaft elongation and anagen induction

Erythropoietin-derived Non-erythropoietic Peptides Conferring Oxidative Stress Resistance to Keratinocytes and Fibroblasts

Investigation on physical and physiological properties of extracellular vesicles derived from Enterococcus faecalis

Structure and function of the keratin 17 tail domain associated with keratin intermediate filament organization

Update on Strategies to Reduce Early Brain Injury after Subarachnoid Hemorrhage

Mitochondrial-targeted therapies in traumatic brain injury: From bench to bedside

Identification and comparison of protein composition of biofilms in response to EGCG from Enterococcus faecalis and Staphylococcus lugdunensis, which showed opposite patterns in biofilm-forming abilities

Antibacterial immunonegative coating with biocompatible materials on a nanostructured titanium plate for orthopedic bone fracture surgery

Comparative proteomics analysis of biofilms and planktonic cells of Enterococcus faecalis and Staphylococcus lugdunensis with contrasting biofilm-forming ability

구조 기반 단백질 설계와 구조생물학의 역할, 그리고 인공지능을 활용한 도구들 Structure-based protein design and useful A.I. tools.

Assessment of the biofilm‑forming ability on solid surfaces of periprosthetic infection‑associated pathogens

Nanostructure-based Wettability Modification of TiAl6V4 Alloy Surface for Modulating Biofilm Production: Superhydrophilic, Superhydrophobic, and Slippery Surfaces

Diabetes mellitus and diabetic foot ulcer: Etiology, biochemical and molecular based treatment strategies via gene and nanotherapy

Second-generation non-hematopoietic erythropoietin-derived peptide for neuroprotection

Effect of Surface Structure Complexity on Interfacial Droplet Behavior of Superhydrophobic Titanium Surfaces for Robust Dropwise Condensation

Ferulic Acid Induces Keratin 6α via Inhibition of Nuclear β-Catenin Accumulation and Activation of Nrf2 in Wound-Induced Inflammation

Structure–function analyses of a keratin heterotypic complex identify specific keratin regions involved in intermediate filament assembly

MAOA variants differ in oscillatory EEG & ECG activities in response to aggression-inducing stimuli

A novel supportive assessment for comprehensive aggression using EEG and ECG

Gender Differences in Aggression-related Responses on EEG and ECG

Transcriptomic analysis reveals Wound healing of Morus alba roots extract by up-regulating keratin filament and CXCL12/CXCL4 signaling

Mathematical modeling of the impact of actin and keratin filaments on keratinocyte cell spreading

Structural basis for heteromeric assembly and perinuclear organization of keratin filaments

Defining Keratin Protein Function in Skin Epithelia: Epidermolysis Bullosa Simplex and Its Aftermath

Modeling the self-organization property of keratin intermediate filaments

Self-organization of keratin intermediate filaments into crosslinked networks

Interaction between the keratin cytoskeleton and eEF1Bgamma affects protein synthesis in epithelial cells

A small surface hydrophobic stripe in the coiled coil domain of type I keratins mediates tetramer stability

Structure and function of the potent cyclic and linear melanocortin analogues

Solution structure of a novel calcium binding protein, MTH1880, from Methanobacterium thermoautotrophicum

Two flexible loops in subtilisin-like thermophilic protease, thermicin, from Thermoanaerobacter yonseiensis

An NMR approach to structural proteomics

Solution structures of the N-terminal domain of histone H4

Minimization of MC1R selectivity by modification of the core structure of alpha-MSH-ND

NMR studies on novel antitumor drug candidates, deoxoartemisinin and carboxypropyldeoxo-artemisinin

DGIST BioInterface Structure and Skin Lab

교수님 소개

이창훈

연구실 소개

연구실 키워드

알럼나이가 간 회사

연구실 지원 방법

대우 조건

연도별 논문 인용수

저널 & 학회 논문 출판 수

연구실 논문 목록

A novel role of erythropoietin in skin pigmentation through melanin production

Expression and Purification of the Ectodomain of Erythropoietin Receptor Fused to mCitrine or mTFP1 Fluorescent Protein in Escherichia coli

A role for Keratin 17 in Rac1-mediated DNA damage response in keratinocytes

연구실 보유 특허

대학별 입시끈

우리 연구실 모집

교수님 소개

이창훈

연구실 키워드

알럼나이가 간 회사

연구실 지원 방법

대우 조건

연도별 논문 인용수

저널 & 학회 논문 출판 수

연구실 논문 목록

A novel role of erythropoietin in skin pigmentation through melanin production

Expression and Purification of the Ectodomain of Erythropoietin Receptor Fused to mCitrine or mTFP1 Fluorescent Protein in Escherichia coli

A role for Keratin 17 in Rac1-mediated DNA damage response in keratinocytes

연구실 보유 특허

최근 3년간 연구실적 높은 연구실

대학별 입시끈

우리 연구실 모집